RNGTT and AP3B1

		RNGTT	AP3B1
Description		RNA guanylyltransferase and 5'-phosphatase	adaptor related protein complex 3 subunit beta 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm
	Molecular Function	MRNA Guanylyltransferase Activity Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding ATP Binding GTP Binding Protein Tyrosine/serine/threonine Phosphatase Activity RNA Guanylyltransferase Activity Triphosphatase Activity	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	7-methylguanosine MRNA Capping RNA Processing Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development
Pathways		RNA Pol II CTD phosphorylation and interaction with CE during HIV infection mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE	Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Colorectal or endometrial cancer ( 26621817) Depression in smokers ( 30219690) Graft survival time in renal transplantation (donor effect) ( 32080893) Height ( 31562340) Response to statin therapy ( 20339536) Simvastatin-induced myopathy ( 31220337) Subcutaneous adipose tissue ( 22589738)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Insulin resistance/response ( 21901158) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Serum alkaline phosphatase levels ( 33547301) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)
Interacting Genes		3 interacting genes: AP3B1 APPBP2 RNMT	19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1
Entrez ID		8732	8546
HPRD ID		04621	04551
Ensembl ID		ENSG00000111880	ENSG00000132842
Uniprot IDs		B4DSJ8 O60942 Q7Z3R6	A0A0S2Z5J4 O00203
PDB IDs		2C46 3S24
Enriched GO Terms of Interacting Partners?
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