KRT38 and PTGER3

Number of citations of the paper that reports this interaction (PubMedID 29892012)
25

Data Source:
BioGRID (two hybrid)

		KRT38	PTGER3
Description		keratin 38	prostaglandin E receptor 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Prostaglandin E Receptor Activity
	Biological Process		Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways		Keratinization Formation of the cornified envelope	Prostanoid ligand receptors G alpha (i) signalling events
Drugs			Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost Castor oil
Diseases
GWAS			Alcohol use disorder (consumption score) ( 33861876) Colon cancer ( 33632709) Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Proximal colorectal cancer ( 33632709) Verbal declarative memory ( 25648963)
Interacting Genes		72 interacting genes: - ABI3 AMOTL2 ANKRD36BP1 BEX2 BRME1 C1orf216 CCDC120 CCDC146 CD300A CEP57L1 DMRT3 DTNB FAM110A FAM90A1 GLRX3 GNG10 GNG13 HAUS1 HDAC4 HGS HMG20B HOXA1 HSF4 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LHX4 LMO3 LMO4 MAGEB4 MAPKBP1 PIK3R2 PIN1 POU4F2 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 SMARCD1 TBC1D21 TRIML2 TXLNA TXLNB TXNDC5 USHBP1 UTP23 ZFYVE21 ZNF20 ZNF417 ZNF587	23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		8687	5733
HPRD ID		05176	08906
Ensembl ID		ENSG00000171360	ENSG00000050628
Uniprot IDs		O76015	O00325 P43115
PDB IDs			6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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