PLPP2 and TRAM1L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP2	TRAM1L1
Description		phospholipid phosphatase 2	translocation associated membrane protein 1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Caveola Integral Component Of Membrane Early Endosome Membrane	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity	Protein Binding
	Biological Process	Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Sphingolipid Biosynthetic Process Phospholipid Dephosphorylation Regulation Of Cell Cycle G1/S Phase Transition	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Insertion Into ER Membrane
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			Bipolar disorder ( 33169155) Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		10 interacting genes: BAG6 HNF4A JAGN1 KMT2A MRPL44 NOTCH2NLA NSG1 TRAM1L1 UNC119 VSTM1	29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2
Entrez ID		8612	133022
HPRD ID		06180	11643
Ensembl ID		ENSG00000141934	ENSG00000174599
Uniprot IDs		O43688	Q8N609
PDB IDs
Enriched GO Terms of Interacting Partners?
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