SCARF1 and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCARF1	CLDN7
Description		scavenger receptor class F member 1	claudin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors	Tight junction interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1	77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MFSD5 MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1
Entrez ID		8578	1366
HPRD ID		06386	07633
Ensembl ID		ENSG00000074660	ENSG00000181885
Uniprot IDs		A8K6Z5 Q14162	A0A384ME58 F5H496 O95471
PDB IDs
Enriched GO Terms of Interacting Partners?
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