DGKZ and RBL1

Number of citations of the paper that reports this interaction (PubMedID 16286473)
11

Data Source:
HPRD (in vivo, in vitro)

		DGKZ	RBL1
Description		diacylglycerol kinase zeta	RB transcriptional corepressor like 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Nuclear Speck Lamellipodium Glutamatergic Synapse	Chromatin Nucleoplasm Transcription Regulator Complex
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Transcription Factor Binding Promoter-specific Chromatin Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Cell Cycle Negative Regulation Of Gene Expression Cell Differentiation Regulation Of Lipid Kinase Activity Regulation Of Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Senescence
Pathways		Effects of PIP2 hydrolysis	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest G1/S-Specific Transcription Cyclin D associated events in G1
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)	Height ( 25429064) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 28957414)
Interacting Genes		19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53	54 interacting genes: AOX1 BEGAIN BRCA1 BRF1 CCNA1 CCNA2 CCND1 CCNE1 CDK2 CDK4 CDK6 CEBPA CREG1 DGKZ DHX30 DYRK1A E2F1 E2F4 E2F5 EPHA2 FN1 GOLGA2 HDAC1 ID2 IRF3 KDM5A KMT5C LAMB2 MAPK6 MCM7 MYBL2 MYC NR2E3 NR4A1 NUCB1 PHB PLSCR1 PPP2R3A RBBP8 RBBP9 RINT1 SMAD2 SMAD3 SMAD4 SMARCA4 SNRPD3 SNW1 SP1 SUV39H1 TAF1 TOP1 TP53BP1 TSC22D2 USP4
Entrez ID		8525	5933
HPRD ID		03260	00312
Ensembl ID		ENSG00000149091	ENSG00000080839
Uniprot IDs		Q13574	P28749
PDB IDs		5ELQ	1H28 4YOO 4YOS 4YOZ 5TUV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?