C1orf94 and PLA2G10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C1orf94	PLA2G10
Description		chromosome 1 open reading frame 94	phospholipase A2 group X
Image		No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Extracellular Region Extracellular Space Lysosome
	Molecular Function	Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Phospholipase Activity Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process		Phospholipid Metabolic Process Phosphatidylserine Metabolic Process Axon Guidance Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Lipid Storage Arachidonic Acid Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Prostaglandin Secretion Low-density Lipoprotein Particle Remodeling Phosphatidylcholine Catabolic Process Cholesterol Homeostasis Regulation Of Macrophage Activation Negative Regulation Of DNA-binding Transcription Factor Activity Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Arachidonic Acid Secretion Defense Response To Virus Lysophospholipid Transport Platelet Activating Factor Catabolic Process Positive Regulation Of Arachidonic Acid Secretion Negative Regulation Of Cholesterol Efflux Positive Regulation Of Acrosome Reaction
Pathways			Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs			Varespladib methyl Crotalus adamanteus antivenin Agkistrodon piscivorus antivenin
Diseases
GWAS		Generalized epilepsy ( 22949513) Lateral ventricle temporal horn volume ( 31530798) Pediatric nonalcoholic steatohepatitis ( 28918882) Sleep duration (short sleep) ( 30846698)	Cholesteryl ester levels ( 31551469) Glycerophospholipid levels ( 26068415)
Interacting Genes		89 interacting genes: ACTN3 AKAP9 ATRIP ATXN1 ATXN1L BANP BOLA1 BOLA2 BOLA2B BOLL BYSL C1orf109 CAMK2A CARD9 CCHCR1 CCNJL CDKN2D CFAP206 CHERP CLK1 CRK CRYBA4 DAB1 DAZAP2 DGCR6 DMRTB1 DOK6 DTX2 FAM168A FHL3 GCC1 GORASP2 GRB2 GSE1 HGS HNRNPF HSF2BP INTS11 IPO11 KLHL32 KRTAP6-2 KRTAP7-1 KRTAP8-1 LCE2C LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB NR3C1 OAZ3 OIP5 PITX1 PLA2G10 PLEKHB2 PRKAG1 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS RFX2 RHOXF2 ROR2 SMAP2 SS18L1 TBX6 TENT5D TLE5 TNPO2 TNS2 TSC1 TXNDC9 UBQLN2 UBQLN4 USO1 VENTX VPS37C YES1	50 interacting genes: AGXT AQP1 ARID5A ATXN1 BAG3 BEX2 C1orf94 CATSPER1 CCDC120 CREB5 CYSRT1 FAM222B FOXH1 GATA5 GNE GRIN2A HGS HOXC8 HR HSF4 INCA1 KPRP KRTAP11-1 KRTAP26-1 LCE1A LCE1C LCE2A LCE2B LCE2D MAL MAPKBP1 MGAT5B MYO10 NOXA1 NTAQ1 OTX1 PITX1 PLA2R1 POU4F3 PPP1R32 ROR2 SNRPC SPAG8 STK16 TBX6 TFG TLX3 VGLL3 VPS37C ZC3H10
Entrez ID		84970	8399
HPRD ID		11310	04674
Ensembl ID		ENSG00000142698	ENSG00000069764
Uniprot IDs		Q6P1W5	O15496
PDB IDs			1LE6 1LE7 4UY1 5G3M 5OW8 5OWC 6G5J
Enriched GO Terms of Interacting Partners?
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