PPFIBP1 and PTPRM

Number of citations of the paper that reports this interaction (PubMedID 9624153)
94

Data Source:
HPRD (in vitro)

		PPFIBP1	PTPRM
Description		PPFIA binding protein 1	protein tyrosine phosphatase receptor type M
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Presynaptic Active Zone	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Cadherin Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Cell Adhesion Neuromuscular Junction Development Synapse Organization	Negative Regulation Of Endothelial Cell Proliferation Protein Dephosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Response To Xenobiotic Stimulus Negative Regulation Of Endothelial Cell Migration Retina Layer Formation Negative Regulation Of Angiogenesis Neuron Projection Development Retinal Ganglion Cell Axon Guidance Peptidyl-tyrosine Dephosphorylation
Pathways		Receptor-type tyrosine-protein phosphatases Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Cerebral cortical growth ( 29682794) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)	Adult body size ( 32376654) Benign childhood epilepsy with centro-temporal spikes ( 32580138) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Dialysis-related mortality ( 21546767) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Glucose homeostasis traits ( 25524916) Hippocampal volume ( 29860282) Huntington's disease progression ( 28642124) Iris heterochromicity ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Recurrence of mild malaria attacks ( 31667592) Response to methotrexate in rheumatoid arthritis ( 24583629) Sitting height ratio ( 25865494)
Interacting Genes		8 interacting genes: PBX2 PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 YWHAG YWHAQ	12 interacting genes: AKAP6 BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1
Entrez ID		8496	5797
HPRD ID		04390	01479
Ensembl ID		ENSG00000110841	ENSG00000173482
Uniprot IDs		A0A024RB02 Q86W92	P28827
PDB IDs			1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
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