UBASH3B and DLGAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBASH3B	DLGAP2
Description		ubiquitin associated and SH3 domain containing B	DLG associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Neurofilament Plasma Membrane Postsynaptic Density Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Phosphoprotein Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Signal Transduction Peptidyl-tyrosine Dephosphorylation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Regulation Of Protein Binding Regulation Of Osteoclast Differentiation Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Aggregation Negative Regulation Of Platelet Aggregation	Neuron-neuron Synaptic Transmission Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576) Blood urea nitrogen levels ( 31152163) Cholesterol, total ( 24097068 25961943 20686565) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Eye length ( 30174134) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 33339817) High light scatter reticulocyte percentage of red cells ( 32888494) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Pemphigus vulgaris ( 29857070) Serum immune biomarker levels ( 32066700) Stroke ( 26089329) Systolic blood pressure ( 30578418) Total cholesterol levels ( 28334899)	Bipolar disorder ( 31043756) Daytime nap ( 33568662) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Stroke ( 32693751) Tau burden ( 33426524) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		51 interacting genes: BBC3 CBL CBLB CCDC74B CUL3 DAZAP2 DISC1 DLGAP2 DMRT3 DOC2A DTX3 EFS FAM168A HOXB2 INCA1 JAK2 KAT5 KDM1A KHDRBS1 KPRP LMO2 LZTS2 MAP3K1 PIAS2 PKP4 PRKN PRR35 PSMB1 PTPN21 RCHY1 REL RNF216 RNF41 SHC1 SLC25A48 SPRY2 SYK TCF4 TEPSIN TNKS TP53BP2 UBB UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B WASL	20 interacting genes: ABI2 ADRB1 CYSRT1 DGCR6 DLG2 DLG3 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 MAGI2 NLGN4X NOS1 PINX1 SHANK2 SHANK3 SORBS2 TSPOAP1 UBASH3B
Entrez ID		84959	9228
HPRD ID		16463	09258
Ensembl ID		ENSG00000154127	ENSG00000198010
Uniprot IDs		Q8TF42	A0A1B0GTN4
PDB IDs		2CPW 2E5K 5VR6 5W5G
Enriched GO Terms of Interacting Partners?
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