BEX2 and SPRY3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BEX2	SPRY3
Description		brain expressed X-linked 2	sprouty RTK signaling antagonist 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Molecular_function Protein Binding
	Biological Process	Apoptotic Process Cell Cycle Signal Transduction Regulation Of Apoptotic Process Regulation Of Cell Cycle	Multicellular Organism Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Axon Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neuron Projection Arborization
Pathways
Drugs
Diseases
GWAS			Idiopathic osteonecrosis of the femoral head ( 28000841) Iron status biomarkers (transferrin saturation) ( 28334935)
Interacting Genes		92 interacting genes: AKAP9 AURKA BCAR3 BHLHB9 BLZF1 BORCS6 BRMS1 CALCOCO2 CCDC197 CCDC57 CCDC85B CCDC88B CDR2 CEP70 COG4 CTAG1A CTAG1B CYSRT1 EXOC8 FGFR2 FSD2 FST HSF2BP HSPB2 HSPB2-C11orf52 KLHL20 KNSTRN KRT15 KRT19 KRT27 KRT31 KRT34 KRT38 KRT39 KRT40 KRT6A KRT75 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-3 KRTAP4-12 KRTAP5-9 KRTAP6-2 KRTAP6-3 LCN2 LDOC1 LMO2 LZTS2 MAGEA11 MAGEA2 MAGEA2B MAGEA4 MDFI MIPOL1 MKRN3 MORN3 MRPL38 MSS51 MTUS2 NECAB2 NFKBID OIP5 OMP PIK3CA PLA2G10 PLEKHG4 PNMA1 PPM1D PRDM14 PTPN11 ROPN1L SERTAD3 SPRED1 SPRY3 SSX2IP SYCE1 TACC3 TRAF1 TRAF2 TRIM27 TRIM42 TRIM69 TRIM73 TRIP6 USHBP1 VPS28 ZDHHC17 ZNF19	27 interacting genes: AQP1 BEX2 CATSPER1 CHRD CREB5 GNE GPSM3 HOXA1 HR KPRP KRT34 LCE1A LCE1B LCE1F LCE2B LCE3A LCE3D LCE3E MAPKBP1 MEOX2 NEK6 R3HDM2 SLC39A7 VSNL1 ZDHHC17 ZNF587 ZNF655
Entrez ID		84707	10251
HPRD ID		06484	03917
Ensembl ID		ENSG00000133134	ENSG00000168939
Uniprot IDs		Q9BXY8	O43610 Q6ZUP3
PDB IDs
Enriched GO Terms of Interacting Partners?
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