SPINK7 and GALNT10

		SPINK7	GALNT10
Description		serine peptidase inhibitor Kazal type 7	polypeptide N-acetylgalactosaminyltransferase 10
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GO Annotations	Cellular Component	Extracellular Region	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Protein O-linked Glycosylation O-glycan Processing
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)	Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)
Interacting Genes		9 interacting genes: EPB42 FTL GALNT10 HBA1 MRPS12 MT1G MT1H MT2A RABL6	7 interacting genes: CNOT2 GEMIN5 LCP2 MUC1 MUC7 SAP30L SPINK7
Entrez ID		84651	55568
HPRD ID		16850	12157
Ensembl ID		ENSG00000145879	ENSG00000164574
Uniprot IDs		P58062	Q86SR1
PDB IDs		2LEO	2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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