PARD6B and RHOQ

Number of citations of the paper that reports this interaction (PubMedID 10934474)
321

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, two hybrid)

		PARD6B	RHOQ
Description		par-6 family cell polarity regulator beta	ras homolog family member Q
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Actin Filament Plasma Membrane Golgi-associated Vesicle Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Protein Kinase C Binding Protein Binding	GTPase Activity Protein Binding Profilin Binding GTP Binding GBD Domain Binding
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly	Endocytosis Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		Tight junction interactions RHOV GTPase cycle	Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	23 interacting genes: BANP CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DHFR DOCK8 EXOC7 GOPC MORN4 NTAQ1 PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL ZNF417
Entrez ID		84612	23433
HPRD ID		18703	05791
Ensembl ID		ENSG00000124171	ENSG00000119729
Uniprot IDs		Q9BYG5	D6W5A7 P17081 V9HWD0
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?
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