CUL4A and SALL2

Number of citations of the paper that reports this interaction (PubMedID 21228219)
8

Data Source:
BioGRID (pull down)

		CUL4A	SALL2
Description		cullin 4A	spalt like transcription factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cullin-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Hemopoiesis Negative Regulation Of Granulocyte Differentiation SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Somatic Stem Cell Population Maintenance Ribosome Biogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Rhythmic Process Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Regulation Of Nucleotide-excision Repair	Eye Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 30061737) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Intracranial aneurysm ( 30823506) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494 27863252) Red cell distribution width ( 32888494)	Fruit consumption ( 32066663) Response to Homoharringtonine (cytotoxicity) ( 25628645) Tuberculosis ( 30713548)
Interacting Genes		25 interacting genes: CAND1 CDKN1B CENPA CHEK1 COMMD1 COPS5 CUL4B DCAF6 DCUN1D4 DDB1 DDB2 H1-2 H3C1 HOXA9 IRS2 RBX1 RNF7 SALL2 SENP8 SKP2 ST7 TUBG1 UBC UBE2E3 UBE2M	8 interacting genes: ADAMTSL4 CEP76 CUL4A CUL4B DDB1 EWSR1 RBBP7 ZMIZ2
Entrez ID		8451	6297
HPRD ID		07218	03743
Ensembl ID		ENSG00000139842	ENSG00000165821
Uniprot IDs		A0A0A0MR50 Q13619	B4DK65 E7EW59 Q9Y467
PDB IDs		2HYE 4A0K
Enriched GO Terms of Interacting Partners?
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