DOC2A and TAOK2

		DOC2A	TAOK2
Description		double C2 domain alpha	TAO kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion	MAPK Cascade Regulation Of Cell Growth Protein Phosphorylation Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Axonogenesis Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Neuron Projection Morphogenesis Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization
Pathways
Drugs			Dexfosfoserine Fostamatinib
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549 32154731) Waist circumference ( 31928498)
Interacting Genes		12 interacting genes: DYNLT1 EIF3C HS3ST4 RAP1GDS1 SCGN STXBP1 TAOK2 TBX6 TGFB1I1 TUFM UBASH3B UNC13B	22 interacting genes: BCKDK CIDEB DOC2A EIF3C ELK1 KLHL12 KRTAP6-3 MAP2K3 MAP2K6 MEGF10 RCHY1 RTRAF SETD1A TLE3 TUBA1A TUBA4A TUBB TUFM USF1 ZNF267 ZNF597 ZNF646
Entrez ID		8448	9344
HPRD ID		05195	18147
Ensembl ID		ENSG00000149927	ENSG00000149930
Uniprot IDs		Q14183	Q9UL54
PDB IDs		4MJJ
Enriched GO Terms of Interacting Partners?
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