MEGF10 and SNRNP200

Number of citations of the paper that reports this interaction (PubMedID 12421765)
41

Data Source:
HPRD (two hybrid)

		MEGF10	SNRNP200
Description		multiple EGF like domains 10	small nuclear ribonucleoprotein U5 subunit 200
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane Integral Component Of Membrane Cell Projection	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)
Interacting Genes		24 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHANK3 SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	34 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B CREBBP DHX38 DUX4 ECT2 EFTUD2 ERG GNMT GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PTEN RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 SUMO2 UBE2I USP19 WBP4 YWHAB YWHAG
Entrez ID		84466	23020
HPRD ID		14384	03391
Ensembl ID		ENSG00000145794	ENSG00000144028
Uniprot IDs		Q96KG7	O75643
PDB IDs			2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9 6S8O 6S8Q 6S9I 7A5P 7ABG 7ABI
Enriched GO Terms of Interacting Partners?
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