HOOK3 and PNMA5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HOOK3	PNMA5
Description		hook microtubule tethering protein 3	PNMA family member 5
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Cis-Golgi Network Centrosome Cytosol Microtubule Centriolar Satellite FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding Identical Protein Binding
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance Protein Localization To Perinuclear Region Of Cytoplasm	Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Zinc levels ( 26025379)
Interacting Genes		13 interacting genes: AKTIP CTIF HOOK1 HOOK2 IDO2 KRT13 KRT27 MAPT MEOX2 MORC3 PNMA5 VPS16 VPS41	59 interacting genes: AP1M1 APPL1 ARPC4 BHLHB9 C11orf49 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CTNNA3 DDX6 DZIP1L EHHADH FOXH1 FSD2 GAS8 GLIPR2 GOLGA6L9 GORASP2 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1
Entrez ID		84376	114824
HPRD ID		09699	06678
Ensembl ID		ENSG00000168172	ENSG00000198883
Uniprot IDs		Q86VS8	Q96PV4
PDB IDs		5J8E 6B9H
Enriched GO Terms of Interacting Partners?
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