PLEKHN1 and PPM1J

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHN1	PPM1J
Description		pleckstrin homology domain containing N1	protein phosphatase, Mg2+/Mn2+ dependent 1J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	Protein Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 31152163) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		45 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CALCOCO2 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PPP1R32 PRICKLE4 PRKAA2 PUSL1 PXN REL RFX6 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1	11 interacting genes: ADORA2A CSN1S1 F2RL1 GPR37 LGALS14 PLEKHN1 PTAFR SMARCD1 SPG21 SUMO1 UBE2I
Entrez ID		84069	333926
HPRD ID		13190	15171
Ensembl ID		ENSG00000187583	ENSG00000155367
Uniprot IDs		Q494U1	Q5JR12
PDB IDs
Enriched GO Terms of Interacting Partners?
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