CTTNBP2 and ARNTL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CTTNBP2	ARNTL2
Description		cortactin binding protein 2	aryl hydrocarbon receptor nuclear translocator like 2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Aryl Hydrocarbon Receptor Complex
	Molecular Function	Protein Binding SH3 Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Dimerization Activity E-box Binding
	Biological Process	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Entrainment Of Circadian Clock Positive Regulation Of Circadian Rhythm Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Myocardial infarction ( 33532862) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (current vs never) ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Sociability score ( 34054130) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Worry too long after an embarrassing experience ( 34054130)	Body fat percentage ( 31752434) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP IMMP2L INCA1 KRT14 MAGEA11 MEI4 PKNOX2	6 interacting genes: CLOCK CTTNBP2 EPAS1 MEOX2 NPAS2 RORC
Entrez ID		83992	56938
HPRD ID		09890	16507
Ensembl ID		ENSG00000077063	ENSG00000029153
Uniprot IDs		Q20BG9 Q8WZ74	Q8WYA1
PDB IDs			2KDK
Enriched GO Terms of Interacting Partners?
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