SPRTN and RNF11

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		SPRTN	RNF11
Description		SprT-like N-terminal domain	ring finger protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Speck	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome
	Molecular Function	Double-stranded DNA Binding Single-stranded DNA Binding Metalloendopeptidase Activity Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Proteolysis Cellular Response To DNA Damage Stimulus Response To UV Protein Autoprocessing Translesion Synthesis Positive Regulation Of Protein Ubiquitination Protein-DNA Covalent Cross-linking Repair	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways		Translesion Synthesis by POLH
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494)	Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)
Interacting Genes		4 interacting genes: POLD3 RNF11 UBC VCPIP1	68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		83932	26994
HPRD ID		13164	09955
Ensembl ID		ENSG00000010072	ENSG00000123091
Uniprot IDs		A0A024R3U2 Q9H040	Q9Y3C5
PDB IDs		5IY4 6MDW 6MDX
Enriched GO Terms of Interacting Partners?
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