SETDB2 and ARL14EP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		SETDB2	ARL14EP
Description		SET domain bifurcated histone lysine methyltransferase 2	ADP ribosylation factor like GTPase 14 effector protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol	Nucleoplasm Nucleolus Cytosol Plasma Membrane Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific)	Protein Binding
	Biological Process	Mitotic Cell Cycle Heart Looping Chromosome Segregation Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Cell Division Histone H3-K9 Methylation Heterochromatin Organization Left/right Axis Specification Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278)	Adult body size ( 32376654) Age at first birth ( 34211149) Chronotype ( 30696823) Heel bone mineral density ( 30598549) Morning person ( 30696823) Polycystic ovary syndrome ( 26284813 30566500) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 30224653)
Interacting Genes		1 interacting genes: ARL14EP	4 interacting genes: HPS5 KANK2 PLEKHF2 SETDB2
Entrez ID		83852	120534
HPRD ID		09712	08796
Ensembl ID		ENSG00000136169	ENSG00000152219
Uniprot IDs		Q96T68	Q8N8R7
PDB IDs		5TFP
Enriched GO Terms of Interacting Partners?
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