C19orf12 and ZNF536

		C19orf12	ZNF536
Description		chromosome 19 open reading frame 12	zinc finger protein 536
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Integral Component Of Membrane Mitochondrial Membrane	Nucleus
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Retinoic Acid-responsive Element Binding Metal Ion Binding
	Biological Process	Autophagy Apoptotic Process Response To Oxidative Stress Mitochondrial Calcium Ion Homeostasis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Height ( 28552196) Response to fenofibrate (total cholesterol levels) ( 27002377)	Adult body size ( 32376654) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Age-related hearing impairment ( 24939585) Atorvastatin-induced myopathy ( 31220337) Body mass index ( 28892062 25673413) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Chin dimples ( 27182965) Chronotype ( 30696823) Falling risk ( 32999390) General risk tolerance (MTAG) ( 30643258) High density lipoprotein cholesterol levels ( 34074324) Major depressive disorder ( 27479909) Myocardial infarction in hypertension (calcium channel blocker interaction) ( 26516778) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Remission after SSRI treatment in major depression ( 30034349) Schizophrenia ( 28991256 25056061 29483656 30285260) Select biomarker traits ( 17903293) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for body mass index ( 27195708)
Interacting Genes		3 interacting genes: APP IKBKG ZNF536	3 interacting genes: C19orf12 POLR2I TSHZ3
Entrez ID		83636	9745
HPRD ID		12696	15825
Ensembl ID		ENSG00000131943	ENSG00000198597
Uniprot IDs		Q9NSK7	O15090
PDB IDs
Enriched GO Terms of Interacting Partners?
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