RAB33B and ATG16L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RAB33B	ATG16L1
Description		RAB33B, member RAS oncogene family	autophagy related 16 like 1
Image
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen Presynapse	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane Vacuole-isolation Membrane Contact Site
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding
	Biological Process	Autophagosome Assembly Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Protein Transport Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER	Autophagosome Assembly Positive Regulation Of Autophagy Protein Transport Macroautophagy Protein Localization To Phagophore Assembly Site Negative Stranded Viral RNA Replication Protein Lipidation Involved In Autophagosome Assembly Xenophagy
Pathways		Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation	Macroautophagy Macroautophagy
Drugs
Diseases
GWAS			Bilirubin levels ( 31801373 31319653 32084209) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		12 interacting genes: ACVR1 ATG16L1 ATG16L2 ATG5 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6	18 interacting genes: APP ATG5 C3 CSNK2A1 CSNK2A2 DEDD2 GAN GIGYF2 NOD1 NOD2 OPTN PLD3 RAB33A RAB33B SCAP SETD7 TRAF3IP3 ZFP36
Entrez ID		83452	55054
HPRD ID		05808	16498
Ensembl ID		ENSG00000172007	ENSG00000085978
Uniprot IDs		A0A494C0Z5 Q9H082	A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5
PDB IDs		6Y09 6ZAY	4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX
Enriched GO Terms of Interacting Partners?
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