FZD7 and SLC30A4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FZD7	SLC30A4
Description		frizzled class receptor 7	solute carrier family 30 member 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane
	Molecular Function	G Protein-coupled Receptor Activity Frizzled Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Stem Cell Population Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Mesenchymal To Epithelial Transition Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Retinoic Acid Negative Regulation Of Cardiac Muscle Cell Differentiation	Response To Toxic Substance Response To Zinc Ion Zinc Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 30598549 28869591) Metabolite levels ( 23823483) Risk-taking tendency (4-domain principal component model) ( 30643258) Total body bone mineral density ( 29304378)	Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		30 interacting genes: ADCY1 AIG1 AQP9 BCL2L13 CCL19 CLN8 CLPTM1 DLG1 DLG2 DLG4 FFAR2 GNAS HPCAL1 LEUTX MAGI3 MGST1 NCALD NCS1 PDAP1 PRKRA PRNP PSME3IP1 SGTA SGTB SLC30A4 SLC35B1 TMEM237 UBQLN1 UBQLN2 UBQLN4	15 interacting genes: BTN2A2 CLN6 CMTM5 FZD7 IER3IP1 LEPROTL1 NDUFAF1 NSG1 PEDS1-UBE2V1 SERP2 TMEM100 TMEM60 TNF TNFRSF10C YIPF6
Entrez ID		8324	7782
HPRD ID		04560	03651
Ensembl ID		ENSG00000155760	ENSG00000104154
Uniprot IDs		O75084	O14863
PDB IDs		4Z33 5T44 5URV 5WBS 6NE2 6NE4 6O3A 6O3B
Enriched GO Terms of Interacting Partners?
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