MADCAM1 and ITGB7

Number of citations of the paper that reports this interaction (PubMedID 9233649)
25

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		MADCAM1	ITGB7
Description		mucosal vascular addressin cell adhesion molecule 1	integrin subunit beta 7
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Exosome
	Molecular Function	Integrin Binding Involved In Cell-matrix Adhesion	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding
	Biological Process	Positive Regulation Of Leukocyte Migration Immune Response Cell Adhesion Cell-matrix Adhesion Signal Transduction Integrin-mediated Signaling Pathway Heterotypic Cell-cell Adhesion Receptor Clustering Leukocyte Tethering Or Rolling Positive Regulation Of Lymphocyte Migration	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell Migration Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Viral Entry Into Host Cell Leukocyte Tethering Or Rolling T Cell Migration
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions
Drugs			R1295 Vedolizumab
Diseases
GWAS			Obesity-related traits ( 23251661) Type 1 diabetes ( 34127860)
Interacting Genes		5 interacting genes: CD44 ITGA4 ITGB7 PIGV STK11	17 interacting genes: CDH1 CYP27B1 DAB1 DOK1 EED FLNA FN1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD RACK1 TLN1 TNS2 VCAM1 ZBTB14
Entrez ID		8174	3695
HPRD ID		00035	00948
Ensembl ID		ENSG00000099866	ENSG00000139626
Uniprot IDs		Q13477	P26010
PDB IDs		1BQS 1GSM 4HBQ 4HC1 4HCR 4HD9	2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?
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