SLC14A2 and LRP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC14A2	LRP10
Description		solute carrier family 14 member 2	LDL receptor related protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane	Plasma Membrane Clathrin-coated Pit Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Cell Adhesion Molecule Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Urea Transport Transmembrane Transport Urea Transmembrane Transport	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Retinoid metabolism and transport
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Bladder cancer ( 24163127) Blood urea nitrogen levels ( 31152163 29403010) Cerebrospinal fluid clusterin levels ( 26545630) Cocaine dependence ( 31212010) FEV1 ( 30804560) Follicular lymphoma ( 25279986) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Intake of total sugars ( 31005972) Lateral orbital frontal cortex volume ( 31530798) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965 28196072) Menarche (age at onset) ( 21102462) Metabolite levels ( 21909109 23823483) Nicotine withdrawal ( 29532581) Nicotine withdrawal symptom count ( 29532581) Pulse pressure ( 28135244 27841878) Red blood cell count ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Systolic blood pressure ( 27841878) Takayasu arteritis ( 33308445) Urate levels ( 31578528)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)
Interacting Genes		12 interacting genes: C4orf3 CMTM7 EHHADH LAT LRP10 PLN PLP2 SEC22A TMEM97 TNF TRARG1 VAMP5	24 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NGDN NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243
Entrez ID		8170	26020
HPRD ID		03366	14311
Ensembl ID		ENSG00000132874	ENSG00000197324
Uniprot IDs		Q15849	Q7Z4F1
PDB IDs
Enriched GO Terms of Interacting Partners?
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