LMAN2L and AQP2

		LMAN2L	AQP2
Description		lectin, mannose binding 2 like	aquaporin 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Lumenal Side Of Membrane
	Molecular Function	Protein Binding Mannose Binding Metal Ion Binding	Water Transmembrane Transporter Activity Protein Binding Glycerol Transmembrane Transporter Activity Water Channel Activity
	Biological Process	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport	Renal Water Homeostasis Renal Water Transport Water Transport Glycerol Transport Cellular Response To Water Deprivation Protein Homotetramerization Transmembrane Transport Cellular Response To Copper Ion Cellular Response To Mercury Ion Metanephric Collecting Duct Development
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER	Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Obsessive-compulsive disorder ( 22889921)
Interacting Genes		8 interacting genes: AQP2 ATP6V1G3 MAL NEURL3 STARD7 TMEM127 USP39 ZDHHC17	61 interacting genes: ACTB BCAP31 C4orf3 CCDC167 CDIPT CERT1 CLCA4 CLDN7 CREB3 CREB3L1 CTSA CXCL16 EEF1A1 EFNA5 ELL2 ERG28 ERGIC3 ERMP1 FAM209A GPAA1 GPX8 IER3 IGFBP5 INSIG2 LEUTX LHFPL5 LMAN2L MRM1 MS4A13 MUC1 NDFIP2 OLFM4 OR10AG1 PANX1 PDZK1IP1 PLP2 PNLIPRP1 RTP2 SLC26A6 SLC30A2 SLC38A7 SLC5A2 SNAP47 SNX5 SPCS1 SSR3 STUB1 STX8 SUPT20H TM9SF2 TMEM109 TMEM218 TMEM230 TMEM236 TMEM60 TMEM86A TMEM97 TRARG1 UBE2J1 VAPB YIPF6
Entrez ID		81562	359
HPRD ID		17286	00141
Ensembl ID		ENSG00000114988	ENSG00000167580
Uniprot IDs		B4DI83 B4DVH1 B4E308 Q9H0V9	P41181
PDB IDs			4NEF 4OJ2 6QF5
Enriched GO Terms of Interacting Partners?
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