POLR2M and LRRK1

Number of citations of the paper that reports this interaction (PubMedID 29513927)
16

Data Source:
BioGRID (pull down)

		POLR2M	LRRK1
Description		RNA polymerase II subunit M	leucine rich repeat kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nuclear Envelope RNA Polymerase II, Core Complex RNA Polymerase II, Holoenzyme Neuronal Cell Body	Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-directed 5'-3' RNA Polymerase Activity	Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	RNA Biosynthetic Process Intracellular Signal Transduction Maintenance Of ER Location	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28552196) Seasonality ( 25562672)	Central corneal thickness ( 32528159 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196) Systemic lupus erythematosus ( 33272962)
Interacting Genes		22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4
Entrez ID		81488	79705
HPRD ID		07575	14319
Ensembl ID		ENSG00000255529	ENSG00000154237
Uniprot IDs		P0CAP1 P0CAP2 Q6EEV4	Q38SD2
PDB IDs		2KXS 6DRD
Enriched GO Terms of Interacting Partners?
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