ANP32A and KPNA1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ANP32A	KPNA1
Description		acidic nuclear phosphoprotein 32 family member A	karyopherin subunit alpha 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Dendrite Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding Histone Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process	Regulation Of DNA Recombination NLS-bearing Protein Import Into Nucleus Skeletal Muscle Satellite Cell Proliferation Satellite Cell Activation Involved In Skeletal Muscle Regeneration Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Postsynapse To Nucleus Signaling Pathway
Pathways		HuR (ELAVL1) binds and stabilizes mRNA	ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Integration of provirus Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Vpr-mediated nuclear import of PICs Inhibition of nitric oxide production
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993)	Calcium levels ( 20705733) LDL cholesterol ( 30275531) LDL cholesterol levels ( 28334899) Mean corpuscular hemoglobin ( 32888494) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		30 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 BBS4 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1	46 interacting genes: ANP32A ANP32B ARNT BCAR3 CD86 CDKN1B CLK4 CRADD CSE1L ELAVL1 EPAS1 FOSL1 GOPC GTF2IRD1 H2BC21 H3-4 HDAC6 HIF1A IL1RAP KPNB1 LEF1 LINC01554 LMO4 MACROD1 MDM2 NMNAT1 NOSIP NUP50 NUP54 NUP62 OGT ORC4 PAX5 PKM POLR3C RAG1 RANBP2 RUNX1T1 SENP2 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5 USP1
Entrez ID		8125	3836
HPRD ID		09014	02819
Ensembl ID		ENSG00000140350	ENSG00000114030
Uniprot IDs		A0A384P5U2 P39687	B3KXZ2 P52294
PDB IDs		2JE0 2JE1 4XOS 6XZQ	2JDQ 3TJ3 4B18 6WX9
Enriched GO Terms of Interacting Partners?
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