IFT88 and ITPKB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IFT88	ITPKB
Description		intraflagellar transport 88	inositol-trisphosphate 3-kinase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Sperm Flagellum Ciliary Tip Ciliary Base Non-motile Cilium	Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Kinesin Binding	Inositol Hexakisphosphate Kinase Activity Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity
	Biological Process	Kidney Development Intraciliary Transport Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Phosphorylation Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Phosphatidylinositol Phosphate Biosynthetic Process Cellular Response To Calcium Ion
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Dentures ( 31235808) Eosinophil percentage of white cells ( 32888494) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 32201043 28892059 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		17 interacting genes: ALDH8A1 CACNA1C CAPN7 CCDC120 EEF2KMT EML2 FBXO7 ITPKB MAP4K5 MSRB1 PCOTH PDX1 PRRC2A RPGR SAP18 SMARCE1 TRIM24	13 interacting genes: CALM1 CEP70 CTDSP1 GOLGA2 IFT88 KRT34 PPP3CA PRKACA PRKCA PSME3 SCAI TRIM54 UBQLN2
Entrez ID		8100	3707
HPRD ID		09000	00942
Ensembl ID		ENSG00000032742	ENSG00000143772
Uniprot IDs		A0A140VJL7 B3KX42 Q13099	B2R9J0 P27987
PDB IDs
Enriched GO Terms of Interacting Partners?
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