DCAF11 and GPSM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DCAF11	GPSM1
Description		DDB1 and CUL4 associated factor 11	G protein signaling modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex
	Molecular Function	Protein Binding	GDP-dissociation Inhibitor Activity Protein Binding
	Biological Process	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways		Neddylation	G alpha (i) signalling events
Drugs
Diseases
GWAS			Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Myocardial infarction ( 33532862) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		13 interacting genes: AGR2 CDKN1A CUL4B DDB1 GPSM1 PTEN RCN1 SLBP TNNI1 TNNI2 TNS2 TRIM55 TRIM63	28 interacting genes: BHLHE40 CCDC158 CTDSP1 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 FXR2 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1
Entrez ID		80344	26086
HPRD ID		18297	17075
Ensembl ID		ENSG00000100897	ENSG00000160360
Uniprot IDs		B3KSW2 Q59GN6 Q8TEB1	A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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