KCNIP4 and TRH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNIP4	TRH
Description		potassium voltage-gated channel interacting protein 4	thyrotropin releasing hormone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex	Extracellular Region Nucleus Plasma Membrane Secretory Granule
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Protein Binding Thyrotropin-releasing Hormone Activity
	Biological Process	Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport	Response To Hypoxia Histamine Metabolic Process Signal Transduction Cell-cell Signaling Response To Cold Response To Glucose Hormone-mediated Signaling Pathway Negative Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Insulin Secretion Eating Behavior Response To Ethanol Response To Corticosterone Negative Regulation Of Feeding Behavior
Pathways		Phase 1 - inactivation of fast Na+ channels	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Colorectal cancer ( 29228715) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 26169577) Diverticular disease ( 30177863) Lingual gyrus volume ( 31530798) Obesity-related traits ( 23251661) Parkinson disease and lewy body pathology ( 25663231) Post bronchodilator FEV1/FVC ratio ( 26634245) Postburn scar height ( 30595539) Rheumatoid arthritis ( 21156761) Suicidal ideation ( 20877300)	Alzheimer's disease ( 30636644) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: APP ASPH COL1A2 GOLGA7 IL17A KCND2 LITAF MEOX2 PSEN1 PSEN2 TRH	8 interacting genes: ARRB2 CD80 CD86 CPE IQCB1 KCNIP4 LCN2 TRHR
Entrez ID		80333	7200
HPRD ID		12184	08944
Ensembl ID		ENSG00000185774	ENSG00000170893
Uniprot IDs		A8K4N3 Q6PIL6	P20396
PDB IDs
Enriched GO Terms of Interacting Partners?
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