EPC1 and MBTD1

Number of citations of the paper that reports this interaction (PubMedID 27153538)
86

Data Source:
BioGRID (affinity chromatography technology, pull down)

		EPC1	MBTD1
Description		enhancer of polycomb homolog 1	mbt domain containing 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Histone Acetyltransferase Activity Protein Binding	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Chromatin Organization Negative Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development
Pathways		HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Sexual dysfunction (female) ( 22509378) Waist-hip index ( 34021172)	Bipolar disorder ( 31043756) Coronary artery disease ( 33020668) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: CHRM5 E2F6 HOPX KAT5 KRT15 MBTD1 NPHP3 RINT1 SYCE1L TRIM27	4 interacting genes: EPC1 H4C1 TULP3 UTP18
Entrez ID		80314	54799
HPRD ID		09941	14369
Ensembl ID		ENSG00000120616	ENSG00000011258
Uniprot IDs		Q9H2F5	Q05BQ5
PDB IDs		6NFX	3FEO 4C5I 6NFX
Enriched GO Terms of Interacting Partners?
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