SCUBE1 and SCUBE2

Number of citations of the paper that reports this interaction (PubMedID 12270931)
38

Data Source:
HPRD (in vitro)

		SCUBE1	SCUBE2
Description		signal peptide, CUB domain and EGF like domain containing 1	signal peptide, CUB domain and EGF like domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane	Extracellular Region Extracellular Space Cell Surface
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Lipid Binding
	Biological Process	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway	Signal Transduction
Pathways		Degradation of the extracellular matrix	Release of Hh-Np from the secreting cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Waist circumference adjusted for body mass index ( 28552196)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Brain morphology (MOSTest) ( 32665545) Hand grip strength (Mahalanobis distance) ( 32235003)
Interacting Genes		4 interacting genes: PMPCA PRR5 SCUBE2 SCUBE3	2 interacting genes: SCUBE1 STK33
Entrez ID		80274	57758
HPRD ID		18029	18030
Ensembl ID		ENSG00000159307	ENSG00000175356
Uniprot IDs		A0JP65 Q6ZS56 Q86TI6 Q8IWY4	B3KS09 Q9NQ36
PDB IDs
Enriched GO Terms of Interacting Partners?
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