PHAF1 and PRR5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PHAF1	PRR5L
Description		phagosome assembly factor 1	proline rich 5 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Trans-Golgi Network Dendrite Synaptic Vesicle Membrane	TORC2 Complex
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Golgi To Plasma Membrane Protein Transport	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Fibroblast Migration Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Response To Oxidative Stress TORC2 Signaling Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31361310 30929738 32296059 31619474) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 26482879 23727859) Body shape index ( 34021172) Hip index ( 34021172) Idiopathic inflammatory myopathy ( 26362759) Inflammatory skin disease ( 25574825) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Photic sneeze reflex ( 27182965) Red blood cell count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		13 interacting genes: APP ATXN3 CBFA2T2 CCDC102B CYB5B ESRP2 KIF17 MPPED1 NPBWR2 PRR5L QSOX1 TOLLIP TSHZ2	15 interacting genes: CCDC91 EFHC1 FHL2 FHL3 HSF2BP KANK2 MAD2L2 MISP MLH1 MORN3 MTOR PHAF1 SCNM1 USP2 ZMYND12
Entrez ID		80262	79899
HPRD ID		17460	07854
Ensembl ID		ENSG00000125149	ENSG00000135362
Uniprot IDs		A0A024R6W4 Q9BSU1	B3KNU3 Q6MZQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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