TM2D3 and SELENOS

		TM2D3	SELENOS
Description		TM2 domain containing 3	selenoprotein S
Image		No pdb structure
GO Annotations	Cellular Component	Spanning Component Of Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex
	Molecular Function		Protein Binding Antioxidant Activity Enzyme Binding Signaling Receptor Activity ATPase Binding Ubiquitin-specific Protease Binding
	Biological Process	Positive Regulation Of Notch Signaling Pathway Lateral Inhibition	Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Gluconeogenesis ER Overload Response Response To Glucose Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Cellular Response To Oxidative Stress Establishment Of Protein Localization Cell Redox Homeostasis Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Response To Redox State Cellular Response To Lipopolysaccharide Regulation Of Nitric Oxide Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Macrophage Apoptotic Process
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Depression in multiple sclerosis (pre-diagnosis) ( 33296963) Triglyceride levels ( 32154731)
Interacting Genes		5 interacting genes: ERRFI1 LRRK1 PAXIP1 SELENOS TARS3	25 interacting genes: APOA5 BLZF1 CD180 CELF4 DERL1 EIF2AK1 ETV7 GTF2IRD1 KLHDC2 KPNB1 LIMK1 LINS1 LRRK1 MFHAS1 NCBP1 OR4F4 SAA1 SNRPA1 SRPK2 SYNM TARS3 TM2D3 TTC23 VCP ZBTB33
Entrez ID		80213	55829
HPRD ID		16554	12133
Ensembl ID		ENSG00000184277	ENSG00000131871
Uniprot IDs		B4DLL2 E7EPS7 H0YNS4 Q9BRN9	Q6GYA4 Q9BQE4
PDB IDs			2Q2F 5KIU 5KIY 6DO4
Enriched GO Terms of Interacting Partners?
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