CEP290 and KIAA1328

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CEP290	KIAA1328
Description		centrosomal protein 290	KIAA1328
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centrosome Centriole Cytosol Membrane Photoreceptor Connecting Cilium Protein-containing Complex Centriolar Satellite Specific Granule Lumen Ciliary Transition Zone MKS Complex Ciliary Basal Body
	Molecular Function	Protein Binding Identical Protein Binding Microtubule Minus-end Binding	Protein Binding
	Biological Process	Kidney Development Protein Transport Hindbrain Development Otic Vesicle Formation Eye Photoreceptor Cell Development Camera-type Eye Development Positive Regulation Of Transcription, DNA-templated Pronephros Development Cilium Assembly Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking Ciliary Transition Zone Assembly Non-motile Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Neutrophil degranulation AURKA Activation by TPX2
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild influenza (H1N1) infection ( 26379185)	Body mass index ( 28552196) Ferritin levels ( 33491795) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Periodontal disease-related phenotype (Socransky) ( 24347629) Reaction time ( 29844566) Simvastatin-induced myopathy ( 31220337) Weight ( 28552196)
Interacting Genes		6 interacting genes: BBLN CC2D2A CREBBP KIAA1328 MAPK10 PICK1	30 interacting genes: AMOT ANKS1A APC ATG5 CARD9 CCDC13 CENPP CEP290 CFAP206 COPB1 DEF6 EAF1 EEF2KMT FAM161A FAM161B GOLGA1 LMO1 LNX1 MTMR9 NEK6 PICK1 PKN1 PRKAA2 SYCE1L TSG101 TSGA10 TTC23 TXLNA TXLNB ZGPAT
Entrez ID		80184	57536
HPRD ID			17211
Ensembl ID		ENSG00000198707	ENSG00000150477
Uniprot IDs		A0A6Q8PGB1 J3KNF5 O15078 Q05BJ6	Q86T90
PDB IDs
Enriched GO Terms of Interacting Partners?
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