VCPIP1 and STX5

Number of citations of the paper that reports this interaction (PubMedID 12473691)
68

Data Source:
HPRD (in vitro, in vivo)

		VCPIP1	STX5
Description		valosin containing protein interacting protein 1	syntaxin 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Lumen Golgi Stack	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Thiol-dependent Deubiquitinase	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Membrane Fusion Protein Ubiquitination Protein Deubiquitination Protein K11-linked Deubiquitination Protein K48-linked Deubiquitination Golgi Reassembly Protein-DNA Covalent Cross-linking Repair Regulation Of Protein Localization To Chromatin	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways		Ovarian tumor domain proteases	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: FCHSD2 GSK3A SMAD9 SNTG2 SPRTN STX5 UBC VAV2 VCP WAC	51 interacting genes: AARD APLP1 AQP6 BAG6 BET1 CCDC153 COPS6 CRB3 CREB3L3 EBP FAM209A GET3 GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STX8 STXBP1 TACC1 TMEM31 TP53 USO1 VAMP5 VAPB VCP VCPIP1
Entrez ID		80124	6811
HPRD ID		15645	04426
Ensembl ID		ENSG00000175073	ENSG00000162236
Uniprot IDs		Q96JH7	B4DKR0 Q13190
PDB IDs			3EFO
Enriched GO Terms of Interacting Partners?
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