STN1 and TEN1

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		STN1	TEN1
Description		STN1 subunit of CST complex	TEN1 subunit of CST complex
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton CST Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm CST Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding Telomeric DNA Binding Single-stranded Telomeric DNA Binding	Single-stranded DNA Binding Protein Binding Telomerase Inhibitor Activity Telomeric DNA Binding
	Biological Process	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Replication	Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity
Pathways		Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation	Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Leukocyte telomere length ( 32109421) Myocardial infarction ( 33532862) Systemic lupus erythematosus ( 33272962) Telomere length ( 33941849) Uterine fibroids ( 31488892 30194396) White matter integrity (mean diffusivity) ( 32358547)	L-selectin levels ( 25576479)
Interacting Genes		19 interacting genes: APP C14orf119 C1orf109 CDK3 GOLGA2 LDLRAP1 LRRK2 MFHAS1 MKRN3 MVP NTAQ1 RCOR3 TEN1 TOLLIP TPP1 TRIML2 TUBGCP4 TXN2 ZDHHC17	1 interacting genes: STN1
Entrez ID		79991	100134934
HPRD ID		14872	19459
Ensembl ID		ENSG00000107960	ENSG00000257949
Uniprot IDs		Q9H668	Q86WV5
PDB IDs		4JOI 4JQF 6W6W	4JOI 6W6W
Enriched GO Terms of Interacting Partners?
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