ERMP1 and KCNN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ERMP1	KCNN3
Description		endoplasmic reticulum metallopeptidase 1	potassium calcium-activated channel subfamily N member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding Metalloexopeptidase Activity Metal Ion Binding	Inward Rectifier Potassium Channel Activity Calmodulin Binding Small Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Ion Transport Potassium Ion Transmembrane Transport
Pathways			Ca2+ activated K+ channels
Drugs			Procaine Miconazole Trimebutine
Diseases
GWAS		Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	Alzheimer's disease in APOE e4- carriers ( 25778476) Atrial fibrillation ( 28416818 29290336 30061737 29892015 20173747 22544366) Bipolar disorder ( 31043756) Birth weight ( 31043758) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 28552196) Incident atrial fibrillation ( 28416818) Interleukin-6 levels ( 33517400) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Prevalent atrial fibrillation ( 28416818) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		38 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MLANA MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	12 interacting genes: APP CALM1 CLCN7 CRABP2 EMD ERMP1 FCER1G HAX1 ILF2 NAPB SLC27A3 UBAP2L
Entrez ID		79956	3782
HPRD ID		17227	04283
Ensembl ID		ENSG00000099219	ENSG00000143603
Uniprot IDs		Q6ZMD3 Q7Z2K6	A0A087WYJ0 Q9UGI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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