DOK3 and PLEKHA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DOK3	PLEKHA3
Description		docking protein 3	pleckstrin homology domain containing A3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane	Golgi Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Phosphatidylinositol-4-phosphate Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction	Biological_process Ceramide Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport
Pathways		Neutrophil degranulation	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Inflammatory bowel disease ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		31 interacting genes: A1CF ABL1 ANKS1A APPL1 APPL2 COX5B CRK CSK DOK1 DOK2 DOK5 DTX2 FYN GCM2 HOXA1 INPP5D LCK LYN MDFI PLEKHA3 PPIH PRKAB2 RBPMS RET RIN3 SHC3 SHE SPAG8 STAT3 TNS2 TRAF1	9 interacting genes: DOK3 ERRFI1 MORF4L1 MRPL45 MYO15B PRKRA RNMT SH2B2 TCL1B
Entrez ID		79930	65977
HPRD ID		16834	09688
Ensembl ID		ENSG00000146094	ENSG00000116095
Uniprot IDs		A0A024R7M5 A0A6M4C8X9 D6RAM3 Q7L591	Q9HB20
PDB IDs			2KCJ 2MDX 3RCP
Enriched GO Terms of Interacting Partners?
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