TFEB and TFEC

Number of citations of the paper that reports this interaction (PubMedID 9806910)
71

Data Source:
HPRD (in vivo)

		TFEB	TFEC
Description		transcription factor EB	transcription factor EC
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Lysosomal Membrane Cytosol	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Embryonic Placenta Development Adaptive Immune Response Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Autophagy Humoral Immune Response Lysosome Organization Cellular Response To Starvation Regulation Of Gene Expression Positive Regulation Of Autophagy Lysosome Localization Cellular Response To Amino Acid Starvation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Blood urea nitrogen levels ( 31152163) Colorectal cancer ( 26965516 30529582) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Late-onset Alzheimer's disease ( 27770636) PR interval ( 32439900) White blood cell count ( 32888494)	Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Intraocular pressure ( 29617998 29785010 29235454) Number of sexual partners ( 30643258) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Tonsillectomy ( 27182965 28928442)
Interacting Genes		5 interacting genes: CD47 MITF SRPK1 TFE3 TFEC	11 interacting genes: DCK DEFB127 HNRNPA1 LPAR3 MITF NAPB SMCO4 TET2 TFE3 TFEB ZMAT2
Entrez ID		7942	22797
HPRD ID		02847	05294
Ensembl ID		ENSG00000112561	ENSG00000105967
Uniprot IDs		A0A024RCY3 B0QYS6 P19484	O14948
PDB IDs
Enriched GO Terms of Interacting Partners?
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