CPLANE2 and RND3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CPLANE2	RND3
Description		ciliogenesis and planar polarity effector 2	Rho family GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Ciliary Basal Body	Golgi Membrane Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Regulation Of Vesicle Fusion Cellular Protein Localization Cilium Assembly	Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways			RND3 GTPase cycle
Drugs			Guanosine-5'-Triphosphate
Diseases
GWAS			Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Daytime nap ( 33568662) Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Platelet count ( 31217584) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)
Interacting Genes		8 interacting genes: CROCCP2 CROCCP3 FUZ IFFO2 IMPDH2 MSLN RND3 TMEM14C	10 interacting genes: ARHGAP5 C14orf119 CDH5 CIT CPLANE2 GCH1 PLXNB1 ROCK1 SKP2 UBXN11
Entrez ID		79363	390
HPRD ID		14399	04233
Ensembl ID		ENSG00000132881	ENSG00000115963
Uniprot IDs		Q9BU20	B2R838 P61587
PDB IDs			1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
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