CENPO and DRC1

		CENPO	DRC1
Description		centromere protein O	dynein regulatory complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex	Cytosol Axonemal Dynein Complex Axoneme Motile Cilium
	Molecular Function	Protein Binding
	Biological Process	Centromere Complex Assembly	Regulation Of Cilium Movement Determination Of Left/right Symmetry Heart Development Cilium-dependent Cell Motility Axonemal Dynein Complex Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		8 interacting genes: CENPP CEP170P1 DCDC2 DRC1 ERI3 FOS FOSB NECAB2	5 interacting genes: C2orf16 CENPO GSK3A TCF23 WDCP
Entrez ID		79172	92749
HPRD ID		14414	11312
Ensembl ID		ENSG00000138092	ENSG00000157856
Uniprot IDs		Q9BU64	Q96MC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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