MLPH and BLOC1S6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MLPH	BLOC1S6
Description		melanophilin	biogenesis of lysosomal organelles complex 1 subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Dendrite Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex Presynapse Axon Cytoplasm
	Molecular Function	Actin Binding Protein Binding Myosin Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Metal Ion Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Intracellular Protein Transport Melanosome Transport	Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Fusion
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Heel bone mineral density ( 30598549 28869591) Height ( 33713608) Intraocular pressure ( 29617998) Prostate cancer ( 21743057)
Interacting Genes		7 interacting genes: BLOC1S6 C1orf216 MTDH MYO5A RAB27A RAB27B RECK	50 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SEMA6D SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3
Entrez ID		79083	26258
HPRD ID		09409	16055
Ensembl ID		ENSG00000115648	ENSG00000104164
Uniprot IDs		A0A024R4D3 Q9BV36	B3KY40 H3BST1 Q9UL45
PDB IDs
Enriched GO Terms of Interacting Partners?
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