FTO and SHC3

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

FTO

SHC3

Description FTO alpha-ketoglutarate dependent dioxygenase SHC adaptor protein 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321)
  • Monocyte count ( 32888494)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Superior parietal cortex volume ( 31530798)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 21 interacting genes: ANKRD11 C1orf109 CCDC57 CLP1 CXCR4 DTX2 EFEMP2 GNG13 GPANK1 IL16 KLHL38 MAD2L2 MORN3 NXF1 OGT PRDM6 SHC3 TNPO2 TTC19 USP20 ZNF77 58 interacting genes: ALK ANKRD10 APP AR ARHGAP32 ASPG AXL BMF CCNC CDCA4 CEACAM6 COPS6 CT55 DOK3 EGFR ERBB2 ERBB3 ERBB4 FLT4 FTO GAB1 GOLGA2 GOLGA6L9 GRB2 KIT KRT31 KRT33B KRT34 KRT35 KRT39 KRT40 KRT86 MET NTRK1 NTRK2 PMF1 PNMA1 PPP1R16B PRKAR1B PSMD8 REL RET SH3GL3 SMYD3 STX11 TRAF1 TRAF2 TRIM35 TRIM54 TSC1 UBAP2 USHBP1 USP54 VPS28 WWOX YPEL3 YPEL5 ZMYND12
Entrez ID 79068 53358
HPRD ID 19057 12005
Ensembl ID ENSG00000140718 ENSG00000148082
Uniprot IDs A0A1B0GTC5 B3KU60 Q99770 Q9C0B1 Q92529
PDB IDs 3LFM 4CXW 4CXX 4CXY 4IDZ 4IE0 4IE4 4IE5 4IE6 4IE7 4QHO 4QKN 4ZS2 4ZS3 5DAB 5F8P 5ZMD 6AEJ 6AK4 6AKW
Enriched GO Terms of Interacting Partners?
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