KCTD15 and WIPI1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD15	WIPI1
Description		potassium channel tetramerization domain containing 15	WD repeat domain, phosphoinositide interacting 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Trans-Golgi Network Cytosol Cytoskeleton Endosome Membrane Extrinsic Component Of Membrane Clathrin-coated Vesicle Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Signaling Receptor Binding Protein Binding Estrogen Receptor Binding Phosphatidylinositol-3-phosphate Binding Androgen Receptor Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Protein Homooligomerization	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Autophagy Cellular Response To Starvation Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Vesicle Targeting, Trans-Golgi To Endosome
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors	Macroautophagy XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 19079260 19079261 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Dental caries (decayed and filled deciduous teeth) ( 31533690) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Disease progression in age-related macular degeneration ( 29346644) Major depressive disorder ( 23377640) Obesity-related traits ( 23251661) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 19079260)	HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		15 interacting genes: ATXN1 CYSRT1 ENSA KCTD1 KCTD21 NBPF19 NOTCH2NLA NOXA1 NTAQ1 REN TFAP2A TRIM27 TRIM55 TRIM63 WIPI1	5 interacting genes: AR ESR1 ESR2 KCTD15 PPA1
Entrez ID		79047	55062
HPRD ID		13765	08540
Ensembl ID		ENSG00000153885	ENSG00000070540
Uniprot IDs		Q96SI1	B4DX63 G5EA37 Q5MNZ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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