CENPM and C22orf46

		CENPM	C22orf46
Description		centromere protein M	CTA-216E10.6
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleoplasm Cytosol	Extracellular Region
	Molecular Function
	Biological Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Meat-related diet ( 32066663) Neuroticism ( 29255261)
Interacting Genes		7 interacting genes: C22orf46 CCDC134 CENPS DESI1 H3C1 PHF5A SEPTIN3	4 interacting genes: APP CENPM KRT40 SMAD2
Entrez ID		79019	79640
HPRD ID		12798	08037
Ensembl ID		ENSG00000100162	ENSG00000184208
Uniprot IDs		A0A024R1Q3 B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4
PDB IDs		4P0T 4WAU
Enriched GO Terms of Interacting Partners?
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