RNF103 and UBE2W

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		RNF103	UBE2W
Description		ring finger protein 103	ubiquitin conjugating enzyme E2 W
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment	Nucleus Nucleoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Central Nervous System Development Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Mannose Trimming	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein
Pathways		ER Quality Control Compartment (ERQC)	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Number of sexual partners ( 30643258)	Cervical high-risk human papilloma virus infection ( 33225922) Malaria ( 31844061) Manganese levels ( 26025379) Urate levels in obese individuals ( 25811787)
Interacting Genes		11 interacting genes: UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2L3 UBE2N UBE2W UBE2Z	80 interacting genes: AKR1C3 AMFR ATXN3 BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CBL CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED ELOC FANCL LRSAM1 MAP3K1 MAPT MARCHF3 MARCHF5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF183 RNF185 RNF2 RNF26 RNF31 RNF4 RNF5 RNF8 ROPN1 SNCA STUB1 TOPORS TRIM17 TRIM2 TRIM23 TRIM27 TRIM31 TRIM35 TRIM39 TRIM5 TRIM59 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID		7844	55284
HPRD ID		03939	07724
Ensembl ID		ENSG00000239305	ENSG00000104343
Uniprot IDs		O00237	Q96B02 Q96FI0 X6REH9
PDB IDs			2A7L 2MT6
Enriched GO Terms of Interacting Partners?
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