DAP3 and TNFRSF10A

Number of citations of the paper that reports this interaction (PubMedID 11376335)
25

Data Source:
HPRD (two hybrid, in vivo)

		DAP3	TNFRSF10A
Description		death associated protein 3	TNF receptor superfamily member 10a
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit	Golgi Apparatus Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Membrane Raft
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding GTP Binding	Protease Binding Death Receptor Activity Protein Binding Transcription Factor Binding Signaling Receptor Activity Identical Protein Binding TRAIL Binding
	Biological Process	Apoptotic Signaling Pathway	Apoptotic Process Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Caspase activation via Death Receptors in the presence of ligand Cell surface interactions at the vascular wall Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TP53 Regulates Transcription of Death Receptors and Ligands Dimerization of procaspase-8 TRAIL signaling
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 21909106 23455636) Attention deficit hyperactivity disorder ( 20732625) Central serous retinopathy ( 31872073) Early age-related macular degeneration ( 32843070)
Interacting Genes		14 interacting genes: AHR AR ESR1 ESR2 FADD HIF1A HSP90AA1 NR3C1 PGR PPARA PTEN THRA TNFRSF10A TNFRSF25	15 interacting genes: BCL10 BTK CASP8 CD4 COL2A1 DAP3 FADD MADD MOAP1 RASSF1 RIPK1 TNFRSF10B TNFRSF10D TNFSF10 TRADD
Entrez ID		7818	8797
HPRD ID		03646	04679
Ensembl ID		ENSG00000132676	ENSG00000104689
Uniprot IDs		P51398	O00220
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K	5CIR
Enriched GO Terms of Interacting Partners?
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