CA6 and SDHB

		CA6	SDHB
Description		carbonic anhydrase 6	succinate dehydrogenase complex iron sulfur subunit B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Extracellular Exosome	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Hydro-lyase Activity	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste One-carbon Metabolic Process	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain
Pathways		Reversible hydration of carbon dioxide	Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		Benzthiazide Cyclothiazide Zonisamide Mafenide Ellagic acid	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Post bronchodilator FEV1 ( 26634245)	Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Hip circumference adjusted for BMI ( 34021172) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		7 interacting genes: FCGRT KRT31 KRT40 MTOR NOTCH2NLA SDHB SLC45A1	16 interacting genes: ABCA1 CA6 CARTPT FLOT1 GEM MFAP2 MSRA PIK3R5 RAP1GAP RPL11 SLC45A1 SLC9A1 SPRY2 STMN1 TARBP1 XRN1
Entrez ID		765	6390
HPRD ID		00264	01707
Ensembl ID		ENSG00000131686	ENSG00000117118
Uniprot IDs		B4DUH8 P23280	P21912
PDB IDs		3FE4
Enriched GO Terms of Interacting Partners?
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