CA3 and HPCAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CA3	HPCAL1
Description		carbonic anhydrase 3	hippocalcin like 1
Image
GO Annotations	Cellular Component	Cytosol	Membrane
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Nickel Cation Binding Phosphatase Activity Hydro-lyase Activity	Calcium Ion Binding Protein Binding
	Biological Process	One-carbon Metabolic Process Response To Oxidative Stress Response To Bacterium Dephosphorylation Response To Ethanol
Pathways		Reversible hydration of carbon dioxide
Drugs		Topiramate Ethoxzolamide Sulpiride Celecoxib Benzthiazide Valdecoxib Cyclothiazide Methazolamide Acetazolamide Dorzolamide Zonisamide Diclofenamide Brinzolamide Ellagic acid Saccharin
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood trace element (Zn levels) ( 23720494) Estimated glomerular filtration rate ( 31152163) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 27863252)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Kidney function decline traits ( 25493955) Lung function (FEV1/FVC) ( 30061609) Platelet distribution width ( 32888494)
Interacting Genes		4 interacting genes: GRM3 HPCAL1 LXN SRC	38 interacting genes: AMOT ATXN1 C19orf44 C1QTNF2 CA3 COLGALT2 CREM DTX2 EFEMP2 EPHB3 FZD7 GATA5 HMG20A IKBKG KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP4-2 KRTAP5-9 LITAF MDFI MICOS10-NBL1 MYDGF NBL1 NBPF19 NOTCH2NLA PLAAT2 SERPINI2 SLC34A1 TPSG1 VWC2 ZNF655
Entrez ID		761	3241
HPRD ID		00260	02564
Ensembl ID		ENSG00000164879	ENSG00000115756
Uniprot IDs		P07451 V9HWA3	O75544 P37235 Q6FGY1
PDB IDs		1Z93 1Z97 2HFW 3UYN 3UYQ	5T7C
Enriched GO Terms of Interacting Partners?
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